Abstract
Silicate composite cements (SCC) composed of Ca3SiO5 and Ca2SiO4 at various proportions were explored with the evaluation of their physicochemical properties and in vitro biocompatibility after hydration. SCC revealed better strength and shorter setting time than pure Ca3SiO5 or Ca2SiO4. The optimal composite with 20 wt% Ca2SiO4 at the liquid-to-powder ratio of 0.5 mL/g was determined for being workable slurries, whose compressive strength achieved 26.4 MPa after one day and 54.1 MPa after 28 days. Furthermore, hydration products of SCC could induce the formation of apatite layer on the surface in simulated body fluid and were compatible with osteoblast-like cells. Thus, SCC have the potential to be self-setting bone-repairing materials.
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