Physicochemical properties and bioactivity studies of synthesized counterion coupled (COCO) gemini surfactant, 1,6-bis(N,N-hexadecyldimethylammonium) adipate

Abstract

In the present investigation, we report the surface activity, micellar, thermodynamic properties and bioactivity studies of synthesized counterion coupled (COCO) gemini surfactant, 1,6-bis(N,N-hexadecyldimethylammonium) adipate (16-6-16). In aqueous solution, the CMC (critical micelle concentration) of 16-6-16 was measured by electrical conductivity, surface tension, dye solubilization and fluorescence measurements techniques. The surface activities and surface properties of the COCO gemini surfactant, 16-6-16 were evaluated. The CMC as well as Amin (the minimum area per surfactant molecule at the air/water interface) decrease and the Γmax (the maximum surface excess concentration at the air/water interface) increases with increasing the temperature. We also report the thermodynamics of 16-6-16 and evaluated Gibbs energies. The aggregation number (Nagg) of 16-6-16 is reported. The bioactivity studies of 16-6-16 showed to be nontoxic, biocompatible and having good antibacterial activity.