Abstract
AbstractRecovery in entomopathogenic nematodes is the exit from the dauer juvenile stage. It is a response to environmental queues signalling the presence of food sources (e.g., insect haemolymph). The bacterium Photorhabdus luminescens excretes a signal which also induces recovery of its symbiotic Heterorhabditis bacteriophora dauer juveniles. This bacterial signal is composed of at least two compounds with different polarity. The symbiotic bacteria also secrete an antagonistic signal which inhibits nematode recovery. The recovery-inducing signal compounds have a molecular mass of less than 20 kDa and are negatively charged. The data indicate that at least one compound is smaller than 5 kDa. The bacterial signal triggers by receptor binding, the first step in a recovery-inducing muscarinic signalling pathway.
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