Abstract
The experiment was conducted to evaluate the acute toxicity of aqueous extract of Adenium obesum stem bark in juveniles of Clarias gariepinus by assessing the hematological responses of the exposed groups compared to the control in a static non-renewal bioassay for 96 hours. The fishes (N = 180, mean weight and length 21.48 ± 3.32 g and 11.37 ± 1.23 cm) respectively were randomly distributed 10 (ten) fishes per group in triplicates constituting six experimental groups as follows; G1 (Control), G2 (6.5 mg/l), G3 (7.8 mg/l), G4 (8.5 mg/l), G5 (9.5 mg/l) and G6 (11.5 mg/l). Red blood cell (RBC) count, packed cell volume (PCV) and hemoglobin concentration were decreased significantly (P Adenium obesum stem bark is toxic to erythrocytes while a converse adaptive response in the white blood cells.
Highlights
Hematological parameters are indicators of stress and give information on the physiological responses of fishes to a changing external environment [1]
The experiment was conducted to evaluate the acute toxicity of aqueous extract of Adenium obesum stem bark in juveniles of Clarias gariepinus by assessing the hematological responses of the exposed groups compared to the control in a static non-renewal bioassay for 96 hours
Oreochromis niloticus exposed to cadmium showed significant reduction in Red blood cell (RBC), Hemoglobin Concentration (Hb) and packed cell volume (PCV) [14]
Summary
Hematological parameters are indicators of stress and give information on the physiological responses of fishes to a changing external environment [1]. The blood parameters have been considered as diagnostic indices of pathological condition as well as important markers for the assessment of systemic functions and overall health of animals. It helps in diagnosing the structural and functional status of animals exposed to the toxicant [9] [10]. This study seeks to investigate the hematological response in Juvenile Clarias gariepinus exposed to aqueous extract of Adenium obesum stem bark in an acute bioassay
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