Abstract

Background: Contagious diseases are the most common cause of death globally and Atisaar is one of them. More than 1 billion cases and at least 4 million deaths per year are attributed to diarrhoea worldwide. Ayurvedic literature has numerous uninvestigated medicines, Shadanga Ghrita is one of those classical herbal formulations used in the management of Atisaar, mentioned in the famous text Chakradatta. Preparation of this oleaginous dosage form is described as Sneha Kalpana, done by subjecting Ghrita to a particular pattern of heat-treated with 1/4th part Kalka (paste) and 4th part of Kwatha (decoction) of the respective drugs in equal proportion. Till date, no research work has been done on the study of Shadanga Ghrita. So the present study was planned to evaluate the Physio-Chemical analysis of Shadanga Ghrita with and without Murchana. Aim and Objective: Aim was to prepare the sample of Shadanga Ghrita with & without Murchana and to evaluate both the formulations through pharmaceutical and analytical parameters. Material and Methods: Murchana of Ghrita was done as per Bhaishajya Ratnavali Jwara-rogadhikaar & Shadanga Ghrita was prepared as per Sharangdhar Samhita. Result: All the Physico-chemical parameters of both the samples are within the reference range Conclusion: Murchita Shadanga Ghrita is better than Amurchita Shadanga Ghrita due to better taste, odor, low viscosity, high saponification & high peroxide value.

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