Abstract
We study the physical properties of model membranes composed of phosphatidylcholines and sterol. The morphology and phase behavior of membranes were investigated by deuterium NMR and fluorescence microscopy. In binary mixtures, coexistence of solid-ordered and liquid-disordered phases was observed in a wide temperature and composition range. The results for ternary mixtures containing sterol show that addition of sterol promotes the formation of the liquid-ordered phase. Sterol has strong influence on the morphology and the phase behavior of membranes. A partial phase diagram of will be presented.
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