Physical Parameters which help in Diagnosis of Urinary Tract Obstruction By Renal Scintigraphy.

Hoda Abdelraouf,Mossad El-Metwally,Hossam Gad

doi:10.21608/ajbas.2020.24150.1011

Hoda Abdelraouf, Mossad El-Metwally + Show 1 more

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https://doi.org/10.21608/ajbas.2020.24150.1011

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Abstract

Background: Diuresis renography is the most commonly test used tool to investigate the urinary tract dilatation, which differentiate between obstructed and non-obstructed systems and evaluate the glomerular filtration rate (GFR). This test is widely accepted because of its convenience and noninvasiveness. Materials and methods: This study included 300 renal units (RU) were examined at Urology and Nephrology Center- Mansoura University from 2016 to 2019 by F+10 min diuretic renography protocol. Results: One hundred and seventeen (RU) of 300 (RU) gave no response to diuresis and were diagnosed as obstructive kidneys. One hundred and twenty one (RU) revealed the excretion of kidneys were delayed but improved diuresis response and were diagnosed as non-obstructive kidneys, The remaining sixty two (RU) showed equivocal response to diuresis after diuretic were done and underwent F-15 min protocol of diuretic renography. Twenty (RU) were proved to be non-obstructed, forty two (RU) showed complete obstruction. Comparing the results of F+10min protocol with F-15 min protocol for the 62 (RU) with equivocal response 42 (RU) revealed as an obstructive kidneys by using F-15min protocol with mean ± SD T½ values 36.64min±14.70min which was 15.19min±2.70 by F+10min (p=.000). The other twenty (RU) revealed as non-obstructive kidneys and have mean ± SD T½ values 9.83min±3.33min by using F-15 min protocol which was 14.43±2.96min by using F+10 min (p=.0.000).

Highlights

Nuclear medicine imaging includes the use of radio-pharmaceuticals which are generally used to detect and assess disease in the human body
The remaining 62 (RU) have mean T1⁄2 value between 10min to 20min with indeterminate diagnosis, this remaining (RU) which showed equivocal response to diuresis were underwent to F-15 min diuretic renography
This patients were examined by the F+10min diuretic renography protocol, 117 (RU) had mean T1⁄2 value more than 20min and diagnosed as obstructed kidneys (Fig 1) and the other 121 (RU) had mean T1⁄2 value less than 10min and diagnosed as non-obstructed, well-functioning kidneys (Fig 2)

Summary

Introduction

Nuclear medicine imaging includes the use of radio-pharmaceuticals which are generally used to detect and assess disease in the human body. Diuresis renography (DR) is a non-invasive, widely available method that used for assessment function of the kidney (GFR) and testing the urodynamics in a single procedure This non-invasive method is depending on a high endogenous urine flow rate which the furosemide being administered; this test always been checked by using radiopharmaceutical washout from the upper urinary tract collecting system [3]. Diuresis renography is the most commonly test used tool to investigate the urinary tract dilatation, which differentiate between obstructed and non-obstructed systems and evaluate the glomerular filtration rate (GFR). This test is widely accepted because of its convenience and noninvasiveness.

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