Abstract
Autism is neuro-developmental disorder. Oxidative stress is enhanced in some children with autism. Hydrogen is a gas with anti-oxidative effects suggested for treating or prevention of some medical problems. It is hypothesized that lactulose or hydrogen water may provide hydrogen to reduce oxidative stress in autism.
Highlights
Autism and oxidative stress Autism is a neurodevelopmental disorder that its diagnosis is increased in recent decade
Oxidative stress probably plays a significant role in the neurobiology of autism [4]
It is supposed that there is a common genetic factor for intestinal and behavioral problems in autism that targeting both problems is recommended for treating autism [30]
Summary
Autism and oxidative stress Autism is a neurodevelopmental disorder that its diagnosis is increased in recent decade. Oxidative stress probably plays a significant role in the neurobiology of autism [4]. Some symptoms of autism are mediated by oxidative stress [5]. Urinary oxidative stress markers levels in autism are more than that of the controls and these levels are associated with the severity of autism [6]. The vulnerability of children with autism to oxidative stress is higher than that of the controls [8].
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