Abstract
Systemic autoimmune myopathies (SAMs) are a heterogeneous group of rare systemic autoimmune diseases that primarily affect skeletal muscles. Patients with SAMs show progressive skeletal muscle weakness and consequent functional disabilities, low health quality, and sedentary lifestyles. In this context, exercise training emerges as a non-pharmacological therapy to improve muscle strength and function as well as the clinical aspects of these diseases. Because many have feared that physical exercise exacerbates inflammation and consequently worsens the clinical manifestations of SAMs, it is necessary to evaluate the possible benefits and safety of exercise training among these patients. The present study systematically reviews the evidence associated with physical training among patients with SAMs.
Highlights
Systemic autoimmune myopathies (SAMs) are a heterogeneous group of rare autoimmune systemic diseases that primarily affect skeletal muscles [1, 2]
Clinical, laboratory, histopathological, and evolutionary data, SAMs can be subdivided into dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM), and others [3]
The descriptors were selected in January 2017 and were defined based on the following keywords: dermatomyositis, inclusion body myositis, polymyositis, idiopathic inflammatory myopathies, aerobic capacity, muscle strength, functional capacity, physical activity, exercise training, resistance training, vascular occlusion training, and resistance training with vascular occlusion
Summary
Systemic autoimmune myopathies (SAMs) are a heterogeneous group of rare autoimmune systemic diseases that primarily affect skeletal muscles [1, 2]. Until the 1960s, absolute rest was recommended for patients with autoimmune rheumatic diseases to help treat the disease [5]. This recommendation has changed because sedentary behavior is known to be associated with increases in triglyceride levels, blood pressure, insulin resistance, and cardiovascular risk [6, 7]. In this context, exercise training emerged as a nonpharmacological therapy for patients with SAMs, thereby contributing to the restoration of the muscle strength and functional capacity of these individuals and improving their clinical condition.
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