Abstract
BackgroundThe aim of the current study is to investigate the relationship between physical anhedonia and psychopathological parameters, pharmacological parameters or motor side-effects in a sample of inpatients with schizophrenia in an acute episode of their illness.MethodEighty one patients with schizophrenia, consecutively admitted, with an acute episode of their illness, at the Eginition Hospital, Department of Psychiatry, University of Athens, during a one-year period were investigated regarding possible relationships between physical anhedonia, social-demographic data and clinical parameters as well as motor side-effects, induced by antipsychotic agents. All patients were assessed using the Chapman Revised Physical Anhedonia Scale (RPAS), the Positive and Negative Syndrome Scale (PANSS), the Rating Scale for Extrapyramidal Side-Effects (EPSE), the Barnes Akathisia Rating Scale (BARS) and the Abnormal Involuntary Movement Scale (AIMS). Simple cross tabulations were initially employed. Subsequently, multiple regression analysis was performed.ResultsBoth positive and negative symptoms were associated with physical anhedonia. A positive association between physical anhedonia and the non-paranoid sub-category of schizophrenia was also proved.ConclusionAccording to these results, it seems that in the acute phase of schizophrenia, physical anhedonia may be a contributing factor to patient's psychopathology.
Highlights
The aim of the current study is to investigate the relationship between physical anhedonia and psychopathological parameters, pharmacological parameters or motor side-effects in a sample of inpatients with schizophrenia in an acute episode of their illness
The aim of the current study was to investigate the relationship between physical anhedonia and social-demographic, clinical parameters as well as motor side-effects in a sample of inpatients with schizophrenia in the acute phase of their illness
The severity of physical anhedonia was significantly related to the diagnostic subcategory of non-paranoid schizophrenia, to the positive symptoms score and to the negative symptoms score of the Positive and Negative Syndrome Scale (PANSS)
Summary
The aim of the current study is to investigate the relationship between physical anhedonia and psychopathological parameters, pharmacological parameters or motor side-effects in a sample of inpatients with schizophrenia in an acute episode of their illness. Rado [4,5] had suggested that anhedonia is a central, genetically transmitted defect both in overt schizophrenia and in compensated schizotypes. PAS: Physical Anhedonia Scale, PANSS: Positive and Negative Syndrome Scale, EPSE: Rating Scale for Extrapyramidal Side-Effects, BARS: the Barnes Akathisia Rating Scale, AIMS: Abnormal Involuntary Movement Scale that anhedonia is an enduring trait, a "cardinal symptom" preceding and possibly causing schizophrenia. Precedes the onset of the disease, represents a defect in the ability to experience physical pleasures, such as pleasures of eating, touching e. T. c., while social anhedonia represents a defect in the ability to experience interpersonal pleasure, such as pleasure of being with people, talking e. Precedes the onset of the disease, represents a defect in the ability to experience physical pleasures, such as pleasures of eating, touching e. t. c., while social anhedonia represents a defect in the ability to experience interpersonal pleasure, such as pleasure of being with people, talking e. t. c
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