Abstract

Background: Many studies have shown a high prevalence of depression, anxiety, and stress symptoms in COVID-19 patients and the general population. However, very few studies directly examined the potential impact on the health-related quality of life (HRQoL), and none compared HRQoL in COVID-19 patients to the general population amid the pandemic.Methods: We carried out a cross-sectional study comparing HRQoL (as measured using the RAND Short Form 36 or SF-36 Health Survey) in randomly selected individuals from three different groups: hospitalized COVID-19 patients, quarantined COVID-19 patients, and controls from the general population in Qatar. We constructed a multivariate analysis of covariance (MANCOVA) to compare the SF-36 scores between the three groups and control for various covariates.Results: Our sample consisted of 141 COVID-19 inpatients, 99 COVID-19 quarantined patients, and 285 healthy controls. Surprisingly, we found that HRQoL was higher in COVID-19 hospitalized than in COVID-19 non-hospitalized patients than in controls. The main components where COVID-patients scored higher than controls were physical functioning and role limitations due to emotional problems. In COVID-19 patients, the female gender, older age, and past psychiatric history were associated with lower HRQoL.Conclusions: It seems that COVID-19 patient's HRQoL might be better than expected. Our results can be explained by social support from family and friends, easy access to mental health screening and care, and a possible change of perspectives after recovery from COVID-19, resulting in psychological growth and enhanced resilience.

Highlights

  • Amidst the Coronavirus disease (COVID-19) pandemic, more reports showed an increase in the prevalence of depressive, stress, and anxiety symptoms in the general population

  • This study aimed to address some of the shortcomings of the previous studies by (i) directly examining the health-related quality of life (HRQoL) amid the pandemic rather than assuming that depressive, anxiety, and stress symptoms translate into poorer HRQoL; (ii) comparing the HRQoL in COVID-19 patients to a sample from the general population group; (iii) comparing two different groups of COVID-19 patients

  • Our sample consisted of 141 inpatients, 99 quarantined individuals with COVID-19, and 285 controls (Table 1)

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Summary

Introduction

Amidst the Coronavirus disease (COVID-19) pandemic, more reports showed an increase in the prevalence of depressive, stress, and anxiety symptoms in the general population. 7.0 to 36.4% of patients endorsed symptoms suggestive of posttraumatic stress disorder (PTSD), and 40.0 to 69.0% reported persistent fatigue 2 to 3 months after discharge, with a significant impact on their activities of daily living and quality of life [3]. All of these symptoms can affect individual’s physical and psychosocial well-being. Very few studies directly examined the potential impact on the health-related quality of life (HRQoL), and none compared HRQoL in COVID-19 patients to the general population amid the pandemic

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