Abstract
Nanomedicines are notably the intriguing strategies for addressing diverse challenges allied with drug delivery. Polymeric micelles, a self-assembled nanocarrier of amphiphilic polymers, help in overcoming drug-related issues like poor solubility and permeability. Diminished size, enhanced solubilization properties, ease of fabrication and sterilization make polymeric micelles more fascinating than other nanocarriers. The first and most imperative step after micelle formation is their characterization which gives detailed information about its size, morphology, critical micellar concentration (CMC), chemical structure, and stability. Characterization is considered the backbone for developing stable, safe, and effective drug delivery systems (DDS). Instead, the benefits of one or more characterization techniques can be further clubbed in order to get better understanding of micelles behavior. This chapter will present a brief description of various physical and analytical characterization techniques for evaluating polymeric micelles.
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