Phthalocyanine‐Based Photosensitizers for Photodynamic Antibacterial Therapy

Abstract

AbstractBacterial infection poses a grave peril to human existence and well‐being, particularly with the emergence of drug‐resistant bacteria, leading to an alarming rise in the incidence of severe illness and mortality. Antimicrobial photodynamic therapy (aPDT) has emerged as one of the most promising strategies for combating bacterial infections due to its potent bactericidal efficacy and non‐inducement of resistance. The development of novel photosensitizers represents a viable approach to further enhance the efficacy of aPDT. Hence, the structural design and application strategies of phthalocyanine‐based photosensitizers were summarized to provide guidance in the development of highly efficient aPDT agents.