Abstract

Objective: Conventional need of broad spectrum antibiotics for multiple organ infections in hospital, ensue the problem of resistance. Most of the antibiotic utilization is empirical leading to their irrational prescriptions. Our present study aims in accessing the drug utilization evaluation of antibiotic usage in a tertiary care hospital which helps in accessing rationality that aid in monitoring the drug efficacy, cost constraints and other factors related to patient safety. Methods: A prospective study was conducted for a period of four months from September 2015 to December 2015 in the Medicine department of Viswabarathi Hospital, Kurnool and AP. Results: A total of 210 prescriptions were analyzed. Among the wide range of antibiotics, i.e., 479 antibiotics prescribed, beta-lactams were found in the maximum cases which accounts for more than half of the cases. Little more than half of the prescriptions i.e.51.90% was with two antibiotics, followed by three antibiotic prescriptions. 9.05% prescriptions were with 4-5 antibiotics. Conclusion: Judgmental use of antibiotics will reduce the burden of multi-drug resistance and thereby enabling better patient management and limiting the resultant morbidity and mortality.

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