Abstract

Vemurafenib has recently been approved for treating advanced melanoma. Targeting the V600 mutation in BRAF , this agent improves progression-free and overall survival of melanoma patients with tumors carrying that mutation. Keratoacanthomas and squamous cell carcinomas (SCCs) are well-known adverse effects of vemurafenib. Two study groups recently characterized other adverse cutaneous reactions in vemurafenib recipients. Gelot and colleagues describe vemurafenib-associated photosensitivity in 10 of 18 previously untreated …

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