Abstract

Selective reaction in molecules which contain more than a single functional group is an essential element in nearly all organic synthesis. Achieving this selectivity can be a challenging problem in reactions of compounds which contain a number of functional groups, particularly if those functional groups are all of the same type (e.g., carbohydrates). Perhaps the most common method for obtaining selective reaction is through the use of protecting groups. One indication of the importance of these groups is the continuing rise in the number of new protecting groups described each year. At present this number appears to be doubling every decade.(1)

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