Abstract
We report a fac–Ir(ppy)3*–IrII–IrIII photocatalytic cycle involving t-BuOK as the terminal reductant in a visible-light-induced sp2 C–F quaternary annulation reaction that proceeds in yields up to 98%. Because of the high activity of the IrII(ppy)3 catalyst, even at a loading of 50 ppm, the annulation reaction was able to compete with an uncatalyzed nucleophilic aromatic substitution reaction. The annulation reaction was stereoconvergent, and an annulated product was synthesized with complete retention of enantiomeric excess.
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