Abstract
At temperate latitudes, organisms use annual changes in daylength (photoperiod) to synchronise seasonal physiology and behaviour. In mammals, photoperiodic responses depend on a master neural circadian pacemaker in the hypothalamic suprachiasmatic nuclei (SCN) [1]. Because circadian rhythm generation depends upon the rhythmic RNA expression of a small group of canonical clock genes [2], it is possible to study the effects of light on oscillations within the SCN by in situ hybridisation histochemistry.
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