Abstract
In pulse oximetry, arterial oxygen saturation (SpO2) is calculated from near-infrared spectroscopy (NIRS) data using the modified Beer-Lambert Law. Tissue homogeneity is assumed, and the photon mean pathlength (〈L〉) needs to be known or calibrated for. We aim to develop a transabdominal fetal pulse oximeter, where SpO2 = 40-70% and the homogeneity assumption and experimental calibration cannot be applied. Our approach relies on spectral fitting of normalized 〈L〉 from NIRS measurements with analytical description of 〈L〉. Data from simulations and human subjects are presented. Our preliminary results show that the self-calibrated algorithm can accurately extract SpO2 changes in homogenous tissue.
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