Abstract
A novel water-soluble [60] fullerene-substituted lysine derivative 3 has been synthesized and characterized by elemental analysis, 1H NMR, 13C NMR and FAB-MS. The synthetic procedure involved condensation of Boc-protected lysine with terephthaldehyde followed by 1,3-dipolar cycloaddition reaction with C60 in the presence of sarcosine and finally deprotection of the amino group using trifluoroacetic acid. The synthesized compound 3 exhibited high DNA cleavage efficiency upon visible light irradiation in the presence of NADH.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
