Abstract
Abstract. In a current study at the University Hospital Dresden, Department of Neurology, the autonomous function of nerve fibres of the human skin is investigated. For this purpose, a specific medicament is applied on a small area of the skin of a test person which results in a local reaction (goose bumps). Based on the extent of the area, where the stimulation of the nerve fibres is visible, it can be concluded how the nerve function of the skin works. The aim of the investigation described in the paper is to generate 3D data of these goose bumps. Therefore, the paper analyses and compares different photogrammetric surface measurement techniques in regard to their suitability for the 3D acquisition of silicone imprints of the human skin. Furthermore, an appropriate processing procedure for analysing the recorded point cloud data is developed and presented. It was experimentally proven that by using (low-cost) photogrammetric techniques medicamentous induced goose bumps can be acquired in three dimensions and can be analysed almost fully automatically from the perspective of medical research questions. The relative accuracy was determined with 1% (RMSE) of the area resp. the volume of an individual goose bump.
Highlights
Photogrammetric methods and image analysis methods are used in medical research and medical practice since a long while the potential of photogrammetric methods is not exploited yet
First aim of the research described in this paper is to investigate and to compare different three-dimensional optical surface measurement techniques regarding their suitability for the recording of 3D point clouds of these silicone imprints, which allow for obtaining the relevant information with the desired accuracy (Chen et al, 2000)
This paper describes and proves experimentally that by using photogrammetric techniques medicamentous induced goose bumps can be acquired in three dimensions and can be analysed almost fully automatically from the perspective of medical research questions
Summary
Photogrammetric methods and image analysis methods are used in medical research and medical practice since a long while the potential of photogrammetric methods is not exploited yet. Second aim is to apply the different measurement techniques to a selection of silicon imprints and to use these data to develop an appropriate processing procedure for analysing the recorded point clouds in terms of medical relevant parameters. Such parameters are for example the total number of goose bumps, the base area and volume of individual bumps as well as the total area and the volume of the whole stimulated region. The recording methods and the developed processing method will be evaluated with regard to their accuracy
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