Abstract
The lethal effect of methylene blue (MB) plus light on extracellular phage T4o is mainly due to lesions in the DNA; the extent of this “DNA-specifity” is about 80% of that of the lethal effect of ultraviolet light. This has been concluded from marker rescue experiments performed with UV-as well as with photodynamically inactivated phages. The difference by a factor of 3.5 in the photodynamic sensitivity of T4o and T4o+ could be referred to the fact that the mutant lacks polyamines, because addition of spermine to T4o increases its resistance at least to the wildtype level. Glucose-containing and glucose-lacking T4-phages show almost the same photodynamic sensitivity so that the difference in the sensitivity of T4 and T2 probably is not due to their various degree of glucosylation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
