Abstract
Among the photosensitizers used in Photodynamic therapy (PDT) technique for cancer treatment, it is found out that the Methylene blue and glycoconjugates chlorine are the best ones for this purpose. In this paper, it is suggested to use Active Capsule Wireless Endoscopy Robot instead of the traditional endoscope. The capsule has many valuable features. It uses LEDs as a source of light in the PDT to kill the colon cancer cells. So, the doctor can make use of the advantage of applying the LED light locally at the tumor which was previously injected by the photosensitizers, the light activates these photosensitizers and a photochemical reaction starts that makes the colon cancer cells die. The light with effective wavelength and power density, energy level and controlled LED light intensity will be applied. Active locomotion capsule endoscopy with an electromagnetic actuation system that can achieve a 3-D locomotion and guidance within the digestive system. The paper also discussed how to manage the required power in the capsule for all parts, LEDs, camera, transceiver, and locomotion.
Highlights
Colon cancer is a type of cancer in the large intestine
Among the photosensitizers used in Photodynamic therapy (PDT) technique for cancer treatment, it is found out that the Methylene blue and glycoconjugates chlorine are the best ones for this purpose
Researchers have focused on photodynamic therapy (PDT), an adjunctive cancer therapy in which lightsensitive tumor- treating drugs which we call photosensitizers are injected by the intravenous
Summary
Colon cancer is a type of cancer in the large intestine (large bowel). Colon cancer can cause several diseases like unexplained weight loss, iron deficiency anemia, blood in stool that may or may not be visible, changes in stool consistency, loose and narrow stools, irritable bowel syndrome, and abdominal pain and cramping [3]. Most cases of colon cancer start from noncancerous tumors called adenomatous polyps that cause no symptoms and it becomes a greater risk of cancer if its diameter becomes greater than 1 cm and if it is not removed, they will grow continuously and can become cancerous [5]
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