Abstract
Objective The evaluation of the effectiveness of topical photodynamic therapy with 5-aminolevulinic acid (5-ALA) and green laser light on superficial basal cell carcinomas.Background Topical photodynamic therapy with exogenous 5-ALA and visible or red laser light has been used up to now for the treatment of superficial non-melanoma skin tumors.Patients and methods Four patients with nine superficial carcinomas participated in this study. The tumors were irradiated with green laser light 5 h after the application of cold cream with 20% aminolevulinic acid under occlusive dressing.Results All nine lesions were resolved with a single treatment and clinical evidence of recurrence was observed in one tumor 1 year after the therapy.Conclusion Topical photodynamic therapy with exogenous 5-ALA and green laser light is very effective for superficial basal cell carcinomas.
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