PHOTODYNAMIC THERAPY AS RESOURCE TO CONTROL OSTEORADIONECROSIS IN ALVEOLAR BONE: A CASE REPORT

Sebastião Silvério De Sousa-Neto,Allisson Filipe Lopes Martins,Marilia Oliveira Morais,Victor Hugo Lopes De Oliveira Moreira,Rodrigo Wilmes Dos Santos,Elismauro Francisco Mendonça

doi:10.1016/j.oooo.2022.01.415

Abstract

A 38-year-old White male smoker for 20 years, diagnosed with lower lip cancer who underwent adjuvant radiotherapy (60 Gy) showed exposure and suppuration of the anterior region of the alveolar mandibular bone after 6 months after radiotherapy treatment. The size of the lesion was ±2 cm and caused fenestration of the buccal mucosa and bony with root exposition. A pulp sensitivity test of the teeth was performed and only teeth 25 and 26 were not vital. Based on radiographic and clinical features, the diagnosis was osteoradionecrosis. Antibiotic therapy (amoxicillin 500 mg), photodynamic therapy (PDT; 660 nm, 12 J/2 cm2, scan), and topical rifocin comprised the treatment established. Previous endodontic treatment was carried out. After 10 sessions of PDT associated with antibiotic therapy the suppuration was reduced, and the osteoradionecrosis was controlled. Rigorous follow-up has been recommended for the patient. PDT is a relevant therapy for the control of osteoradionecrosis. A 38-year-old White male smoker for 20 years, diagnosed with lower lip cancer who underwent adjuvant radiotherapy (60 Gy) showed exposure and suppuration of the anterior region of the alveolar mandibular bone after 6 months after radiotherapy treatment. The size of the lesion was ±2 cm and caused fenestration of the buccal mucosa and bony with root exposition. A pulp sensitivity test of the teeth was performed and only teeth 25 and 26 were not vital. Based on radiographic and clinical features, the diagnosis was osteoradionecrosis. Antibiotic therapy (amoxicillin 500 mg), photodynamic therapy (PDT; 660 nm, 12 J/2 cm2, scan), and topical rifocin comprised the treatment established. Previous endodontic treatment was carried out. After 10 sessions of PDT associated with antibiotic therapy the suppuration was reduced, and the osteoradionecrosis was controlled. Rigorous follow-up has been recommended for the patient. PDT is a relevant therapy for the control of osteoradionecrosis.

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