Abstract

We previously reported on the outcome of 21 patients with stage IV advanced and/or recurrent tongue base carcinoma subjected to mTHPC-PDT. We continue to develop on the previous work by treating more patients with this unforgiving disease. PDT has shown to be a very successful minimally-invasive surgical tool in managing this pathology. Tumour-associated symptoms were reduced significantly. The overall morbidity and mortality following PDT, in this group of patients, were far less when compared with other conventional modalities.

Highlights

  • IntroductionIn a preliminary study, on the use of PDT as a minimally-invasive surgical intervention for advanced and/or recurrent tongue base carcinoma [1]

  • We previously reported on the outcome of 21 patients with stage IV advanced and/or recurrent tongue base carcinoma subjected to mTHPC-PDT

  • The overall morbidity and mortality following PDT, in this group of patients, were far less when compared with other conventional modalities

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Summary

Introduction

In a preliminary study, on the use of PDT as a minimally-invasive surgical intervention for advanced and/or recurrent tongue base carcinoma [1]. Twenty-one patients with this unforgiving disease were subjected to mTHPC-US-guided interstitial PDT, the cohort was followed-up for a mean of 36 months Tumour response to PDT was remarkable with the majority of the patients reporting reduction of tumour-associated symptoms (P

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