Abstract

AbstractThe aesthetic effects of photodynamic therapy (PDT) for photoaged skin are well documented in clinical studies. An improvement of lentigines, skin roughness, sallow complexion, and fine wrinkles was demonstrated. Reduction of histological signs of photoaging as a decrease of elastotic material and expression of p53 was shown together with the induction of neocollagenesis. PDT represents a promising technique for skin rejuvenation because this therapy effectively improves photoaged skin, allows repeated treatment sessions, has only limited and calculable side effects, and offers the possibility of contemporaneously treating non-melanoma skin cancer.

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