Abstract
To explore nitric oxide (NO)-donating capability of Roussin’s red ester [Fe2(μ-RS)2(NO)4] (RRE), photodissociation of NO from RRE and its subsequent reaction dynamics were probed by monitoring the N–O stretching mode after excitation with a 400-nm photon. As a result of the experiment, the NO generation quantum yield was obtained.
Highlights
Nitric oxide (NO) is an important cell signalling molecule involved in many physiological and pathological processes and is a potent vasodilator with a short half-life in the blood [1,2]
Quantum yield for NO generation, and solubility of Roussins red ester (RRE) are related to the thiol molecule used [3]
We were able to identify reaction intermediates in the photolysis and establish subsequent reactions of the intermediates as well as photodissociated NO with nascent photoproducts. These observations can be utilized to identify optimal thiol molecule used in synthesis of RRE for better stability and higher NO quantum yield, which can serve getting requirement for a better NO donor
Summary
Nitric oxide (NO) is an important cell signalling molecule involved in many physiological and pathological processes and is a potent vasodilator with a short half-life in the blood [1,2]. Various thiol molecules were used to synthesize RRE. Quantum yield for NO generation, and solubility of RRE are related to the thiol molecule used [3].
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