Abstract
A variety of fluorescence-labeled DNA oligomers have been developed for gene analysis. We have studied on the development of a new functional fluorescent DNA probe for decrease in false positive signals. Thiazole orange derivatives were designed for the fluorescent label of DNA oligomers. The DNA oligomer containing a thiazole orange dye exhibited fluorescence with a higher intensity on hybridization with a complementary RNA, compared with that from the oligomer alone.
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