Abstract
AbstractAlkylation of naphthoquinones (NQs) and phenothiazinone (PTZs) was achieved through chemo‐selective functionalization of different mono/di‐alkyl amides in the presence of photocatalyst eosin‐y and TBHP under the influence of blue light (Blue LEDs) as an energy source, at room temperature to get the products in moderate to good yield. These highly conjugated alkylated compounds displays absorption and emission in the visible region, has potential to be used as fluorescent probes and other light harvesting materials. Insilico study revealed that some of these compounds are potential phosphodiesterase‐4B (PDE4B) inhibitors and has excellent drug like properties. Furthermore, the cytotoxic activity of alkylated quinones toward human lung cancer cell line (A549) was studied.
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