Abstract

Abstract Fe 3 O 4 –TiO 2 core-shell nanocomposites were successfully prepared and characterized by FE-SEM, XRD, UV–vis absorbance spectra, and EDX. The FE-SEM and EDX studies revealed core-shell structure with a particle size of ca. 40–50 nm. We adopted HeLa cells as a model to investigate the thermal-photocatalytic cell killing efficiency of Fe 3 O 4 –TiO 2 using 150 μg/mL dose content for 10 min exposure time. We found neither only AC magnetic-field induction nor only photoirradiation condition could kill the cancer cells up to satisfactory level using Fe 3 O 4 –TiO 2 nanocomposites. Finally, the results revealed that almost 100% cancer cells were destructed by Fe 3 O 4 –TiO 2 nanocomposites whereas for bare Fe 3 O 4 and bare TiO 2 , 90% and 56% cancer cells were killed, respectively, under combined AC (alternating current) magnetic-field induction and UV–vis photoirradiated conditions.

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