Abstract
The regiospecific and stereoselective photocatalysed addition of N-substituted pyrrolidines to 5(S)-substituted furan-2-(5H)-ones (butenolides), and subsequent conversion of the adduct from N-(trimethylsilyl)pyrrolidine into the 1-azabicyclo[3.3.0]octane ring system of the pyrrolizidine alkaloids are described.
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More From: Journal of the Chemical Society, Perkin Transactions 1
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