Abstract
Photobiomodulation is a noninvasive modality with significant anti-inflammatory effects. Because there is no drug interaction, it is an alternative for patients with systemic impairment and polypharmacy. A 46-year-old female patient diagnosed with phenytoin-induced toxic epidermal necrolysis presented typical fever and erythematous bullous lesions on the trunk, limbs, face, and mouth. In addition, an increase in C-reactive protein, leukocytes, and procalcitonin and positive Nikolsky sign were detected. The treatment was conducted by a multidisciplinary team with pharmacological and supportive measures for the lesions. The stomatognathic system showed lesions in the vermilion of the upper and lower lips, buccal mucosa, and palate, compromising communication, hygiene, and diet, which was done via nasoenteral tube. After low-level laser therapy by the hospital dentistry team, the patient evolved with regression of oral lesions and changed to an oral diet. Despite the high mortality rates of this condition, the present case progressed favorably for hospital discharge and the patient remains in follow-up.
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