Abstract
Gold nanoparticles can be used as an exogenous contrast agent for biomedical photoacoustic (PA) imaging. The generation of PA signals in monodispersed gold nanosphere suspensions (diameters 20–150 nm) from pulsed-laser excitation (5 ns pulse width, wavelength 532 nm) was investigated experimentally and compared to signals measured in solutions of a homogeneous molecular absorber. The PA signal amplitude was found to increase linearly with excitation fluence for the homogeneous absorber and the nanospheres up to 80 nm in diameter. By contrast, the signal amplitude was found to increase quadratically with respect to fluence for larger nanospheres. In the linear regime, the PA signal amplitude in gold nanosphere suspensions was found to be on average 26% higher than that in the homogeneous absorber with identical absorption coefficient, which were measured using an integrating sphere. Furthermore, in suspensions with identical absorption coefficient, no dependence of the PA signal amplitude on nanosphere dia...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
