Abstract
In this review article, a detailed chronological account of the research related to photoacoustic imaging for the management of breast cancer is presented. Performing a detailed analysis of the breast cancer detection related photoacoustic imaging studies undertaken by different research groups, this review attempts to present the clinical evidence in support of using photoacoustic imaging for breast cancer detection. Based on the experimental evidence obtained from the clinical studies conducted so far, the performance of photoacoustic imaging is compared with that of conventional breast imaging modalities. While we find that there is enough experimental evidence to support the use of photoacoustic imaging for breast cancer detection, additional clinical studies are required to be performed to evaluate the diagnostic potential of photoacoustic imaging for identifying different types of breast cancer. To establish the utility of photoacoustic imaging for breast cancer screening, clinical studies with high-risk asymptomatic patients need to be done.
Highlights
The number of breast cancer cases was largest among the different types of cancers, considering male and female populations together, and it was the leading cause of cancer-induced deaths among women in 2015 [1]
Invasive or infiltrating breast cancers can spread to other parts of the body, and they are comprised of invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) [2]
This study indicates that over the last two decades, as far as breast cancer detection is concerned, PA imaging systems have been significantly improved by customizing US detector assembly as well as scanning configurations
Summary
The number of breast cancer cases was largest among the different types of cancers, considering male and female populations together, and it was the leading cause of cancer-induced deaths among women in 2015 [1]. Non-Invasive breast cancers are those which do not spread, and comprise ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS). Invasive or infiltrating breast cancers can spread to other parts of the body, and they are comprised of invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) [2]. For American women, it is the second leading cause of deaths due to cancer [3,4]. The American Cancer Society estimated that the number of new female IBC cases in the United States for 2019 would be 268,600 in addition to
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