Photoacoustic Imaging: An IR820 Dye–Protein Complex for Second Near‐Infrared Window and Photoacoustic Imaging (Advanced Optical Materials 4/2020)

Abstract

After mixing a sulfonated NIR-I organic dye (IR820) with human serum albumin (HAS), fluorescence in the biological NIR-II window of the IR820–HSA organic complex increases dramatically, as shown by Yaming Li, Zhen Cheng and co-workers in article number 1901471. In vivo NIR-II imaging with IR820–HSA can noninvasively and dynamically be used to visualize and monitor the physiological and pathological conditions of the vascular system, lymphatic drainage system, and tumor-bearing mice, as well as allow image-guided tumor resection.