Photo‐Induced Functionalization of para‐Benzoquinones: Access to Dihydroquinoxalines with a Tetrasubstituted Carbon Stereocenter

Abstract

Visible light induced activation of para-benzoquinone, and its sequential coupling with alkynes and ortho-phenylenediamines/ortho-aminophenols is reported. The protocol provides a route for synthesizing value-added quinoxaline derivatives with tetrasubstituted carbon stereocenter at room temperature in 36–75% yields. Mechanistic investigation suggests that the reaction proceeds via in-situ generation of para-quinone methide through direct excitation of para-benzoquinone in blue light. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.