Photo‐Controllable Catalysis and Chiral Monosaccharide Recognition Induced by Cyclodextrin Derivatives

Abstract

AbstractA supramolecular catalytic system was constructed from polycationic α‐cyclodextrin (6‐Iz‐α‐CD) and gold nanoparticles (AuNP) using a supramolecular assembly strategy. The cavity of cyclodextrin is the channel by which the substrate molecules come into contact with the catalytic center. Introduction of the azobenzene‐modified diphenylalanine (Azo‐FF) guest molecule allowed for precise photo‐control of the catalytic activity owing to its sensitive response to irradiation. Importantly, as a unique glucose oxidase the AuNP@6‐Iz‐α‐CD realizes unprecedented chiral recognition catalysis for chiral monosaccharides. In combination with a 3,3′,5,5′‐tetramethylbenzidine (TMB) color reaction, AuNP@6‐Iz‐α‐CD is able to recognize the chirality of various monosaccharides.