Abstract
Neutron reflectivity was applied to monitor in situ the adsorption of small unilamellarphospholipid vesicles on a solid bare hydrophilic Si interface. The obtained reflectivitycurves are consistent with the rupture and fusion model for the adsorption ofphosphatidylcholine vesicles to solid interfaces. The results show details of the adsorbedbilayer system at ångström resolution and indicate the presence of a thin thick water leaflet that separates the bilayer from the Si surface. The resolved structuraldetails provide the basis for further investigation of processes such as adsorption andpenetration of peptides and proteins towards the supported bilayer at high resolution.
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