Abstract
Changes in phosphoinositide metabolism due to muscarinic stimulation of the adrenal medulla are reviewed. Evidence is presented that muscarinic receptors inhibit catecholamine secretion by the bovine gland and that muscarinic agonists do not cause entry of calcium ions. Results are inconsistent with the theory that phosphatidylinositol hydrolysis opens calcium ‘gates’. Polyphosphoinositide metabolism is also reviewed and the suggestion made that phosphatidylinositol 4,5-bisphosphate may regulate the activity of the calcium pump ATPase in cells where phosphoinositide-linked receptors promote calcium influx.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
