Abstract

Contactless manipulation of particles and cells using acoustic forces that can be adjusted in real time is now important in $e.g.$ biomedical sensors, imaging devices, and diagnostic tools. Dynamic manipulation typically requires huge phased arrays with complex electrical control, or a moving source with an inflexible displacement platform, but here the authors develop a method using an acoustic field modulated by a phononic crystal plate (PCP) in an acoustofluidic channel. PCP resonance-based dynamic manipulation via a single source, by switching the frequency, has the advantages of being simple, disposable, scalable, and combinable with a microfluidic chip.

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