Abstract

Proton-ligand stability constant, metal-ligand stability constants, pK and log k of azelastine hydrochloride with Cu(II), Co (II) and Fe(II) metal ions were determined by pH-metric technique. Irving-Rossotti titration technique was used for determination of stability constants. 1:1 complexes were formed in present investigation in between azelastine hydrochloride (TH) and Cu (II), Co (II) and Fe (II) metal ions.

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