Abstract

1. 1. A case of phlegmasia cerulea dolens is reported. 2. 2. Massive venous occlusion is associated with a defibrinogenation of the circulating blood. 3. 3. An hypothesis is forwarded that a pancreatic carcinoma, a cryofibrinogen and the pathogenesis of phlegmasia cerulea dolens may be related. 4. 4. The pain of this disease process is probably due to an acute anoxic state involving the muscles of the lower extremity. 5. 5. The gangrene is due to the complete thrombosis of all the veins acting as an internal tourniquet on the diseased leg.

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