Phish-Pharm: A Searchable Database of Pharmacokinetics and Drug Residue Literature in Fish - 2022 Update.

Abstract

A new version of Phish-Pharm: a Searchable Database of Pharmacokinetics and Drug Residue Literature in Fish has been updated and posted online at: http://www.fda.gov/AnimalVeterinary/ScienceResearch/ToolsResources/Phish-Pharm/default.htm . The new version contains over 700 articles encompassing 191 aquatic species (fish, shellfish, and more).Phish-Pharm, first released in 2005, accompanied an article in this Journal, titled "Fish Drug Analysis-Phish-Pharm: A Searchable Database of Pharmacokinetics Data in Fish," by R. Reimschuessel, L. Stewart, E. Squibb, K. Hirokawa, T. Brady, D. Brooks, B. Shaikh, C. Hodsdon, AAPS Journal. 2005;07(02):E288-E327, article 30. ( https://link.springer.com/article/10.1208/aapsj070230 )FDA understands that there are limited approved, conditionally approved, or indexed drugs available for use in aquatic animals. In response, FDA made this reference database publicly available to assist investigators in developing new animal drugs for aquatic species. The database also supports FDA Center for Veterinary Medicine's mission of protecting human and animal health by serving as a resource for the aquatic drug approval process and drug residue surveillance.Phish-Pharm is a Microsoft Access database that is periodically updated. Searchable fields include pharmacokinetic data and links to the abstract for each article. Phish-Pharm enables users to evaluate information on drugs and chemicals and to identify research gaps to guide future research. Phish-Pharm is not intended for aquaculture farmers to evaluate safety or effectiveness of unapproved drugs. Phish-Pharm is not an appropriate tool for recommending withdrawal intervals of drug and chemical residues due to variability among studies. Aquaculture farmers should only use approved, conditionally approved, or indexed drugs in their operations (see Approved Aquaculture Drugs ).