Abstract

We report three cases of pheochromocytoma of the bladder and review the literature. Often, the clinical manifestations of this rare neoplasm are elusive; however, a classic triad of symptoms, initiated by voiding, is well documented. Current localizing diagnostic modalities include measurement of plasma and urinary catecholamines, cystoscopy, computed tomographic (CT) scanning, andm[131I]iodobenzylguanidine (MIBG) radioactive scanning. When feasible, the treatment of choice is partial cystectomy, with appropriate control of blood pressure and blood volume. Histologic determination of malignancy is equivocal and can complicate therapeutic options. Postoperative follow-up is required, as recurrence has been observed.

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