Abstract
A case of pheochromocytoma complicating pregnancy is described. In addition to the suggestive clinical symptoms, definite diagnosis was based on the estimation of urinary catecholamines and vanillyl mandelic acid (VMA). Treatment with phentolamine permitted fetal viability to be reached. The tumor was removed immediately following cesarean section. No ill effects of the tumor secretions on the fetus could be observed Plasma levels of norepinephrine were high in the mother but low in the fetus, whereas VMA was elevated in the fetal blood as compared to the maternal blood, suggesting placental and/or fetal transformation of maternal catecholamines. The activities of 13 enzymes and the distribution of glycogen and lipids were investigated in the tumor.
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