Abstract
A monoselenium containing diBODIPY-based probe was synthesized. The probe was found to be selective and sensitive for the detection of superoxide (KO2) over other reactive oxygen species through fluorescence turn-on event with 11-fold increase in fluorescence intensity. The detection limit was found to be 4.42 μM. The utility of the probe for detection of intracellular superoxide was demonstrated in a mammalian breast cancer cell line (MCF-7) through fluorescence microscopy.
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