Abstract
Two new phenylpropionic acid derivates, cerberic acids A ( 1) and B ( 2), were isolated from the bark of Cerbera manghas. Their structures were established on the basis of spectroscopic methods including IR, ESI-FT-ICR-MS, 1D and 2D NMR. Primary bioassays showed that compound 1 possessed weak cytotoxic activity against HepG2, MCF-7, and HeLa cell lines with IC 50 values of 44.7, 52.3, 48.7 μg/ml, respectively.
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