Abstract

Plasma concentrations of free and conju-gated phenylacetic acid, the major meta-bolite of phenylethylamine, were higher in ten prisoners serving long terms of imprisonment for violent crimes than in pair-matched non-violent control prisoners. Since amphetamine, a compound closely related to phenylethylamine, can reduce aggressiveness in some violent subjects, the increase in phenylethylamine pro-duction may be an attempt to compensate for the un-known derangement of function responsible for in-creased aggression.

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