Abstract
The article is devoted to the study of spirographic indicators FEV1, FEV1/FVC, PEF, MEF75, MEF50, and MEF25 as the most informative indicators reflecting the state of bronchial patency at the level of the proximal and distal portions of the bronchial tree in various phenotypes of occupational asthma. The signs of respiratory distress are most pronounced in patients with the occupational COPD phenotype of occupational asthma. Significantly more favorable spirographic picture in terms of FVC, FEV1, PEF, and MEF25VC is observed in the allergic phenotype of occupational asthma. Dynamic determination of forced expiratory flow in various phenotypes of occupational bronchial asthma allows to improve the diagnosis of obstructive disorders in this pathology, optimize the choice of therapeutic and preventive tactics, and predict the course of this pathology.
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